BIOLOGICAL AND THERAPEUTIC RELEVANCE OF THE DISCOVERY OF PROSTACYCLIN AND NITRIC OXIDE

J Pharm Pharmacogn Res 2(Suppl. 1): S1, 2014

Special supplement with the abstract book of LATINFARMA 2013

Plenary Lecture

PL 001: BIOLOGICAL AND THERAPEUTIC RELEVANCE OF THE DISCOVERY OF PROSTACYCLIN AND NITRIC OXIDE

Moncada S.

The Wolfson Institute for Biomedical Research, University College London, United Kingdom.
Abstract

In this lecture I will explain how the mechanism of action of aspirin and other non-steroidal anti-inflammatory drugs were discovered and will also describe the discovery of prostacyclin and nitric oxide. I will discuss the biological relevance of those discoveries to our understanding of the physiology and pathophysiology of various organs and tissues and their implications for the therapy and prevention of different diseases. Finally I will consider the possibilities of future research in these areas of research.