PACH-75: BACTERICIDAL ACTIVITY OF PLANT Wedelia trilobata L. PRELIMINARY STUDY OF THE TYPES OF METABOLITES PRESENT IN ITS EXTRACTS

J Pharm Pharmacogn Res 3(suppl. 1): S168, 2015

Proceedings of the 4th International Symposium on Pharmacology of Natural Products FAPRONATURA 2015  September 21st-25th, 2015; Cuban Society of Pharmacology. Topes de Collantes, Sancti Spiritus, Cuba.

Poster

PACH-75: BACTERICIDAL ACTIVITY OF PLANT Wedelia trilobata L. PRELIMINARY STUDY OF THE TYPES OF METABOLITES PRESENT IN ITS EXTRACTS

Pérez C1, Echemendía OA2, Spengler I1, García T1.

1Center for Natural Product Studies, Faculty of Chemistry, Havana University, Cuba. E-mail: elvira@fq.uh.cu
2Finlay Institute, Havana, Cuba.

 

Introduction: Plants are a valuable resource in the health systems of developing countries. The World Health Organization has estimated that more than 80% of the world population, uses traditional medicine for their primary health care needs and that much of the traditional treatments involve the use of extracts of plants or their active ingredients. The plant Wedelia trilobata L. known in Cuba as “camomile of garden” is widely disseminated in our territory, specifically in gardens and parterrier, as it has very showy yellow flowers. In the literature appears reported bactericide activity of n-hexane from the stems of this plant crude, so us performed the evaluation of the bactericide activity of the crude of n-hexane and ethanol obtained from the leaves and the study of the types of metabolites in both crudes. Material and Methods: The dried ground plant material was extracted by decoction using n-hexan and subsequently with ethanol. Both extract were concentrations and the identification of the types of metabolites was performed using the Rondina and Cossio method. The evaluation of the bactericide activity of the extracts from n-hexane and ethanol were performed at concentrations from 500 mg/mL up to 31.25 mg/mL using disk diffusion method to determine antibacterial sensitivity, according to the rules of the standard laboratories Committee (NCCLS). Results and Conclusions: N-hexane crude showed bactericide activity against the strains Staphylococuus aureus, Staphylococuus cuagulasa negativo, Acinetobacter liroffi, while the ethanolic showed no activity. N-hexane crude is rich in triterpenes-steroids, alkaloids, and quinones, while the ethanolic triterpenes-steroids, flavonoids and glycosides.

 

Citation Format: Pérez C, Echemendía OA, Spengler I, García T (2015) Bactericidal activity of plant Wedelia trilobata L. Preliminary study of the types of metabolites present in its extracts. [Abstract]. In: Proceedings of the FAPRONATURA 2015; 2015 Sep 21-25; Topes de Collantes, Sancti Spiritus: CSF. J Pharm Pharmacogn Res 3(Suppl. 1): S168. Abstract nr PACH-75.