J Pharm Pharmacogn Res 3(suppl. 1): S149, 2015
Proceedings of the 4th International Symposium on Pharmacology of Natural Products FAPRONATURA 2015 September 21st-25th, 2015; Cuban Society of Pharmacology. Topes de Collantes, Sancti Spiritus, Cuba.
PCT-57: PHARMACOVIGILANCE OF PHYTOMEDICINES AND APIMEDICINES, MATANZAS 2005 – 2014
Santos L, Marín N, Sánchez D, Hidalgo M.
Introduction: Cuba has developed further phytomedicines and apimedicines used in a wide range of diseases. The current investigation has the purpose to characterize the adverse reactions associated with the use of phytomedicines and apimedicines sold in Matanzas from 2005 to 2014. Method: observational descriptive and retrospective study of pharmacovigilance. The sample consisted of all the reports on suspected adverse drug reactions caused by phytomedicines and apimedicines submitted to the Provincial Pharmaco-vigilance Coordinating Unit during the study period. Results: Most reports on suspected adverse reactions corresponded to the female sex (68.9 %) and the 20-59 age group (57.6 %). The phytomedicines most frequently reported were garlic tincture and syrup (32.9 %), oregano (Plectranthus amboinicus [Lour] Spreng.), (21.8 %), and eucalyptus syrup and tincture (15.4 %), whereas the most frequently reported apimedicine was propolis tincture (18.6%). The digestive system was the most commonly affected by adverse reactions (69.2%). In the causality assessment, the highest percentage of adverse effects was classified as probable (76.8%). According to the national behaviour of the suspicions of adverse reactions and severity, the moderate reactions were the most notified (60.3 %), followed by the mild. There was no mortal adverse effect. Conclusions: It is important that specialists provide appropriate instructions about the use of medicinal plants.
Citation Format: Santos L, Marín N, Sánchez D, Hidalgo M (2015) Pharmacovigilance of phytomedicines and apimedicines, Matanzas 2005 – 2014. [Abstract]. In: Proceedings of the FAPRONATURA 2015; 2015 Sep 21-25; Topes de Collantes, Sancti Spiritus: CSF. J Pharm Pharmacogn Res 3(Suppl. 1): S149. Abstract nr PCT-57.