PHARMACOLOGICAL MANAGEMENT OF NEUROPATHIC PAIN

J Pharm Pharmacogn Res 2(Suppl. 1): S114, 2014

Special supplement with the abstract book of LATINFARMA 2013

Plenary Lecture

PL 010: PHARMACOLOGICAL MANAGEMENT OF NEUROPATHIC PAIN

Granizo E.

Universidad Central de Ecuador.
Abstract

Patients with neuropathic pain are challenging to manage and evidence-based clinical recommendations for pharmacologic management are needed. In the last years the scientific information on pharmacological treatment of neuropathic pain has increase considerably. In the present review we take into account some groups of drugs classified by their site and mechanism of action: peripheral receptors; b) peripherals nerve fibers, c) spinal pain modulators, d central descendent modulators (re-up take amines inhibitors) and opioids, tramadol. We will review the recommended first line treatment include certain antidepressants, gabapentinoids, and topic lidocaine. Opioid analgesics and tramadol are recommended as generally second-line treatments that can be considered for first –line use in select clinical circumstances. We consider useful to give some concepts of the guidelines and recommendations from “Consenso Latinoamericano para el Manejo del Dolor Neuropático”