J Pharm Pharmacogn Res 3(suppl. 1): S100, 2015
Proceedings of the 4th International Symposium on Pharmacology of Natural Products FAPRONATURA 2015 September 21st-25th, 2015; Cuban Society of Pharmacology. Topes de Collantes, Sancti Spiritus, Cuba.
PPP-08: A PHARMACO TOXICOLOGICAL STUDY OF THE EXTRACTS OBTAINED FROM THE PLANTS Tagetes lucida CAV. AND Lippia alba MILL. ELABORATED IN THE INSTITUTE OF PHARMACY AND FOODS OF THE UNIVERSITY OF HAVANA
García G, Casanova M, Jorge N, Gutiérrez Y, Sánchez A, Scull R, Pardo GL.
Introduction: We denominated medicinal plants to those plants whose parts or extracts are used like drugs or medicine for the treatment of some affection or illness that suffers an individual or animal, among them we can mention Tagetes lucida Cav. and Lippia alba Mill. Material and Methods: In our work we carried out the pharmacological assay to demonstrate the analgesic effect of the T. lucida and the anti-inflammatory effects of the L. alba, both assay are described by the CYTED. On the other hand, the tests of oral and dermal acute toxicity were made to T. lucida and L. alba respectively by the procedures that are described in the Economic Organization for the Cooperation and Development (OECD). Results: The pharmacological assay showed that T. lucida presented similar results that the Aspirin, use as pattern, for the analgesic effects. On the other hand, when we studied the anti-inflammatory effect of the L. alba we used as pattern the cream of indometacina both showed similar effects. In the case of dermal and oral acute toxicity for the studied extracts, we use the dose limit assay of 2000 mg/kg. No deaths neither clinical signs were presented, as well as damages in the organs of the rats, for that reason we can classified inside the range according to the European Union of: without classification. Conclusions: Both extracts possess the attributed pharmacological effects and that they did not present acute toxicity when the doses limit assay was used.
Citation Format: García G, Casanova M, Jorge N, Gutiérrez Y, Sánchez A, Scull R, Pardo GL (2015) A pharmaco toxicological study of the extracts obtained from the plants Tagetes lucida Cav. and Lippia alba Mill. elaborated in the Institute of Pharmacy and Foods of the University of Havana. [Abstract]. In: Proceedings of the FAPRONATURA 2015; 2015 Sep 21-25; Topes de Collantes, Sancti Spiritus: CSF. J Pharm Pharmacogn Res 3(Suppl. 1): S100. Abstract nr PPP-08.