Probiotics: A new resource for gastrointestinal disorders

J Pharm Pharmacogn Res 7(3): 193-199, 2019.

Review | Revisión

Probiotics and gastrointestinal diseases: A promising complementary medicine resource for treatment of gastrointestinal disorders and diseases

[Probióticos y enfermedades gastrointestinales: un prometedor nuevo recurso de la medicina complementaria para el tratamiento de trastornos y enfermedades gastrointestinales]

Khatereh Anbari1, Majid Firouzi2, Saber Abbaszadeh3,4,5,6*

1Community Medicine Department, Lorestan University of Medical Science, Khorramabad, Iran.
2Department of Pediatrics, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
3Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
4Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
5Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
6Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.

*E-mail: saberabaszade1370@gmail.com

Abstract

Context: Probiotics are living microorganisms (bacteria or yeasts) whose swallowing in an appropriate number has beneficial effects on host health and improves the host microflora. Different types of digestive diseases are treated by probiotics, including inflammatory gastrointestinal diseases, functional gastrointestinal disorders, irritable bowel syndrome and ulcerative colitis.

Aims: To analyze the role of the effect of probiotics on gastrointestinal disorders, especially intestinal illness.

Methods: Articles related to “probiotics and digestive disorders and diseases” were searched in citation databases including PubMed, Institute for Scientific Information, Scopus, Google Scholar and Magiran. The search strategy was based on the terms “probiotics and gastrointestinal disorders”. Clinical trials and systematic reviews regarding the effects of probiotics on the prevention and treatment of gastrointestinal diseases were included. Irrelevant articles were deleted, and the rest of the articles were used to conduct review.

Results: Lactobacillus rhamnosus GG, Bifidobacterium lactys, Streptococcus thermophilus, Saccharomyces boulardii, Escherichia coli Nissle, Probiotic VSL#3, Bacillus coagulants, Lactobacillus acidophilus and Streptococcus thermophilus are one of the most important probiotics that affect gastrointestinal disorders.

Conclusions: According to the findings found in this review from clinical trials regarding the effects of probiotics on the prevention and treatment of gastrointestinal diseases, there is evidence that the probiotics have beneficial effects on the gastrointestinal disorders.

Keywords: diseases; disorders; gastrointestinal; probiotics; remedies.

Resumen

Contexto: Los probióticos son microorganismos vivos (bacterias o levaduras) cuya ingestión en un número apropiado tiene efectos beneficiosos sobre la salud del huésped y mejora la microflora del huésped. Los diferentes tipos de enfermedades digestivas se tratan con probióticos, que incluyen enfermedades gastrointestinales inflamatorias, trastornos gastrointestinales funcionales, síndrome de intestino irritable y colitis ulcerosa.

Objetivos: Analizar el papel del efecto de los probióticos en trastornos gastrointestinales, especialmente enfermedades intestinales.

Métodos: Se buscaron artículos relacionados con “probióticos y trastornos y enfermedades digestivas” en las bases de datos de citas, incluyendo PubMed, Instituto de Información Científica, Scopus, Google Académico y Magiran. La estrategia de búsqueda se basó en los términos “probióticos y trastornos gastrointestinales”. Se incluyeron ensayos clínicos y revisiones sistemáticas sobre los efectos de los probióticos en la prevención y el tratamiento de enfermedades gastrointestinales. Se eliminaron los artículos irrelevantes y el resto de los artículos se utilizaron para realizar la revisión.

Resultados: Lactobacillus rhamnosus GG, Bifidobacterium lactys, Streptococcus thermophilus, Saccharomyces boulardii, Escherichia coli Nissle, Probiotic VSL # 3, Bacillus coagulants, Lactobacillus acidophilus y Streptococcus thermophilus, son los probióticos más importantes que afectan los trastornos gastrointestinales.

Conclusiones: De acuerdo con los hallazgos encontrados en esta revisión de ensayos clínicos sobre los efectos de los probióticos en la prevención y el tratamiento de enfermedades gastrointestinales, existe evidencia de que los probióticos tienen efectos beneficiosos en los trastornos gastrointestinales.

Palabras Clave: desórdenes; enfermedades; gastrointestinal; probióticos; remedios.

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Citation Format: Anbari K, Firouzi M, Abbaszadeh S (2019) Probiotics and gastrointestinal diseases: A promising complementary medicine resource for treatment of gastrointestinal disorders and diseases. J Pharm Pharmacogn Res 7(3): 193–199.

© 2019 Journal of Pharmacy & Pharmacognosy Research (JPPRes)