Assessing pharmaceutical patents with the index of internal effort

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J. Pharm. Pharmacogn. Res., vol. 12, no. 5, pp. 852-869, Sep-Oct 2024. DOI: https://doi.org/10.56499/jppres23.1859_12.5.852 Review Bridging the gap in patent assessment: The Index of Internal Effort framework for pharma innovations [Bridging the gap in patent assessment: The Index of Internal Effort framework for pharma innovations] Alisson A. de Oliveira1*, Celso B. dos Santos2, Luiz A. … Continue reading Assessing pharmaceutical patents with the index of internal effort

J. Pharm. Pharmacogn. Res., vol. 12, no. 5, pp. 852-869, Sep-Oct 2024.

DOI: https://doi.org/10.56499/jppres23.1859_12.5.852

Review

Bridging the gap in patent assessment: The Index of Internal Effort framework for pharma innovations

[Bridging the gap in patent assessment: The Index of Internal Effort framework for pharma innovations]

Alisson A. de Oliveira1*, Celso B. dos Santos2, Luiz A. Pilatti3

1Federal Institute of Education of Paraná (IFPR), Curitiba, Paraná, Brazil.

2State University of Ponta Grossa (UEPG), and Federal University of Technology – Paraná (UTFPR), Ponta Grossa, Brazil.

3Postgraduate Program in Production Engineering (PPGEP), Federal University of Technology – Paraná (UTFPR), Ponta Grossa, Brazil.

*E-mail: alisson.oliveira@ifpr.edu.br, alissonantonio@yahoo.com.br

Abstract

Context: The process of assessing patents is complex, and there is a gap in the literature on patent assessment at the time of filing.

Aims: To assess patent complexity and the human effort involved in research, we test the effectiveness of the Index of Internal Effort (IIE) framework using pharmaceutical patents developed within the Brazilian public sector as a proof of concept.

Methods: Internal data were collected from innovation projects that included the filing of patents as a project outcome. The Spearman correlation test was applied to determine which internal patent variables could be used as metrics in IIE. Then, IIE was used to measure the complexity of the patents and the individual effort of inventors. Results were then compared with other metrics identified in the literature.

Results: The IIE showed a positive and significant correlation with resources invested at the design stage, as well as commercial and social outcomes of the patents.

Conclusions: The results indicate that the generic IIE framework is a new form of metrification that can be applied to pharmaceutical patents that have not been previously discussed in the literature.

Keywords: data science; Fiocruz; intellectual effort; patent; pharmacology; public service.

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Resumen

Contexto: El proceso de evaluación de patentes es complejo, y existe un vacío en la literatura sobre la evaluación de patentes en el momento de su presentación.

Objetivos: Evaluar la complejidad de las patentes y el esfuerzo humano implicado en la investigación, la eficacia del marco del Índice de Esfuerzo Interno (IIE), utilizando patentes farmacéuticas desarrolladas dentro del sector público brasileño como prueba de concepto.

Métodos: Se recogieron datos internos de proyectos de innovación que incluían la presentación de patentes como resultado del proyecto. Se aplicó la prueba de correlación de Spearman para determinar qué variables internas de las patentes podían utilizarse como métricas en la IIE. A continuación, se utilizó la IIE para medir la complejidad de las patentes y el esfuerzo individual de los inventores. A continuación, se compararon los resultados con otras métricas identificadas en la bibliografía.

Resultados: La IIE mostró una correlación positiva y significativa con los recursos invertidos en la fase de diseño, así como con los resultados comerciales y sociales de las patentes.

Conclusiones: Los resultados indican que el marco genérico IIE es una nueva forma de metrificación que se puede aplicar a las patentes farmacéuticas que no se han discutido previamente en la literatura.

Palabras Clave: ciencia de datos; esfuerzo intelectual; farmacología; Fiocruz; patente; servicio público.

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Citation Format: de Oliveira AA, Santos CB, Pilatti LA (2024) Bridging the gap in patent assessment: The index of internal effort framework for pharma innovations. J Pharm Pharmacogn Res 12(5): 852–869. https://doi.org/10.56499/jppres23.1859_12.5.852
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