Category Archives: anthelmintic

Potentials of Bombax ceiba thorn extract

J Pharm Pharmacogn Res 5(1): 40-54, 2017.

Original Article | Artículo Original

Pharmacognostic and pharmacological studies of Bombax ceiba thorn extract

[Estudios farmacognóstico y farmacológico del extracto de espina de Bombax ceiba]

Manish A. Kamble, Debarshi Kar Mahapatra*, Disha M. Dhabarde, Ashwini R. Ingole

Department of Pharmacognosy, Kamla Nehru College of Pharmacy, Nagpur – 441108, Maharashtra, India.



Context: Bombax ceiba is a large deciduous tree found in tropical and sub-tropical regions of Asia, Africa, and Australia. Traditional systems of medicine such as Ayurveda, Siddha and Unani have been highlighted the use of B. ceiba parts (bark, leaves, and flower) for the treatment of numerous ailments like algesia, hepatotoxicity, hypertension, HIV infections, fever, dysentery, inflammation, catarrhal affection, ulcer, acne, gynecological disorders, piles and urinary infections. However, no scientific pharmacognostic, phytochemical and pharmacological study has been reported for B. ceiba thorn.

Aims: To study the pharmacognostic and pharmacological potentials of B. ceiba thorn extract.

Methods: The physicochemical properties were determined using pharmacopoeial tests. The phytochemical screening was carried out using standard protocols. The in vitro anti-inflammatory activity was performed by human red blood cells stabilization method, in vitro anthelmintic activity by Pheretima posthuma method, in vitro antioxidant activity by DPPH scavenging method, and anti-microbial studies by agar streak dilution method against bacteria E. coli, B. subtilis, K. pneumonia, and fungi C. albicans and A. niger.

Results: The hydroalcoholic thorn extract of Bombax ceiba (TEBC) showed significant anti-inflammatory (46.9% stabilization), anthelmintic (death at 59.22 min), in vitro anti-oxidant (41.62% inhibition), and anti-microbial activities (B. subtilis > E. coli > K. pneumonia; A. niger > C. albicans).

Conclusions: The study revealed the physicochemical, photochemical and pharmacognostic features of thorn of the B. ceiba. The study also revealed the possession of different pharmacological potentials of extract.

Keywords: anthelmintic; anti-inflammatory; antimicrobial; Bombax ceiba; pharmacognosy; thorn extract.


Contexto: Bombax ceiba es un árbol de hoja caduca que se encuentra en las regiones tropicales y subtropicales de Asia, África, y Australia. Los sistemas tradicionales de la medicina como Ayurveda, Siddha y Unani han puesto de relieve el uso de las partes de B. ceiba (corteza, hojas y flores) para el tratamiento de numerosas enfermedades como la sensibilidad dolorosa, hepatotoxicidad, hipertensión, infecciones por VIH, fiebre, disentería, inflamación, catarros, úlceras, acné, trastornos ginecológicos, hemorroides y las infecciones urinarias. Sin embargo, no hay estudios científicos farmacognósticos, fitoquímicos y farmacológicos sobre la espina de B. ceiba.

Objetivos: Estudiar las potencialidades farmacognósticas y farmacológicas de extracto de espina de B. ceiba.

Métodos: Las propiedades fisicoquímicas se determinaron mediante pruebas reportadas en la farmacopea. El tamizaje fitoquímico se llevó a cabo utilizando protocolos estándar. La actividad anti- inflamatoria in vitro se realizó mediante el método de estabilización de glóbulos rojos humanos, la actividad antihelmíntica in vitro por el método de Pheretima posthuma, la actividad anti-oxidante in vitro por el método de secuestro de DPPH y los estudios anti-microbianos por el método de dilución en agar contra las bacterias E. coli, B. subtilis, K. neumonía y hongos C. albicans y A. niger.

Resultados: El extracto hidroalcohólico de espina de Bombax ceiba (TEBC) mostró significativa actividad anti- inflamatoria (46.9% de estabilización), vermífuga (muerte en 59.22 min), anti-oxidante (41.62% de inhibición) y anti-microbiana (B. subtilis > E. coli > K. pneumoniaA. niger > C. albicans).

Conclusiones: El studio reveló las características fisicoquímicas, fitoquímicas y farmacognósticas de la espina de B. ceiba. También reveló las potencialidades farmacológicas del extracto.

Palabras Clave: anti-inflamatorio; antimicrobiano; Bombax ceiba; extracto de la espina; farmacognosia; vermífugo.

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Citation Format: Kamble MA, Mahapatra DK, Dhabarde DM, Ingole A (2017) Pharmacognostic and pharmacological studies of Bombax ceiba thorn extract. J Pharm Pharmacogn Res 5(1): 40-54.
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