CO 051: OPIOIDS UPDATE IN 2013. PAIN FREE HOSPITALS, IMPORTANCE OF ITS DEVELOPMENT IN CUBA

Excerpt:


J Pharm Pharmacogn Res 2(Suppl. 1): S28, 2014 Special supplement with the abstract book of LATINFARMA 2013 Oral Communication CO 051: OPIOIDS UPDATE IN 2013. PAIN FREE HOSPITALS, IMPORTANCE OF ITS DEVELOPMENT IN CUBA Yera-Nadal JL. Clínica del Dolor Hospital Hermanos Ameijeiras, La Habana, Cuba. E-mail: joyena@infomed.sld.cu Abstract Opioids are still important analgesics in the … Continue reading CO 051: OPIOIDS UPDATE IN 2013. PAIN FREE HOSPITALS, IMPORTANCE OF ITS DEVELOPMENT IN CUBA

J Pharm Pharmacogn Res 2(Suppl. 1): S28, 2014

Special supplement with the abstract book of LATINFARMA 2013

Oral Communication

CO 051: OPIOIDS UPDATE IN 2013. PAIN FREE HOSPITALS, IMPORTANCE OF ITS DEVELOPMENT IN CUBA

Yera-Nadal JL.

Clínica del Dolor Hospital Hermanos Ameijeiras, La Habana, Cuba. E-mail: joyena@infomed.sld.cu
Abstract

Opioids are still important analgesics in the management of acute and chronic pain. They can be very effective and also safe if used wisely, with a thorough understanding of their pharmacology. Opioids often cause adverse effects; respiratory depression and nausea are important adverse effects when opioids are used to treat acute pain, whereas constipation, cognitive impairment, hormonal effects, addiction and tolerance are relevant concerns in chronic administration. However, nothing like nonsteroidal anti-inflammatory drugs, there are not evidences of severe injury on vital organs as heart, liver and kidney by its long term use. In the present review it discussed the use of opioids in acute and chronic pain, with focus in MOR agonists as morphine, oxycodone, fentanyl, methadone, hydromorphone and buprenorphine, particularly in the news special routes and modes of administration. We also analyzed the importance of nonopioid effects that are relevant for its analgesic profile. For example, racemic methadone and its ability by binding to N-methyl–D aspartate (NMDA) receptor, that exhibit noncompetitive antagonism. As well as, tramadol and tapentadol, which also inhibit the reuptake of monoamines. Moreover, it will provide up to date information regarding the pharmacokinetic and pharmacogenetic differences among opioids. On the other hand we are considering about the importance of accepting pain as a vital sign and then develop pain free hospitals in our country. This information can be used to improve the effective and safe use of available opioids in the management of pain and it also offers possibilities for improving opioid efficacy and reversing opioid tolerance.

Phyllanthus emblica flavonoid glycosides against xanthine oxidase
J. Pharm. Pharmacogn. Res., vol. 12, no. 6, pp. 1067-1078, Nov-Dec 2024. DOI: https://doi.org/10.56499/jppres24.1959_12.6.1067 Original Article Antioxidant potential and xanthine oxidase inhibition of flavonol glycosides from Phyllanthus emblica L. leaves [Potencial antioxidante e inhibición de la xantina oxidasa de los glucósidos de flavonol de las hojas de Phyllanthus emblica L.] Husnunnisa1, Rika Hartati1, Rachmat Mauludin2, … Continue reading Phyllanthus emblica flavonoid glycosides against xanthine oxidase
Spray-drying Perilla frutescens extract optimization
J. Pharm. Pharmacogn. Res., vol. 12, no. 6, pp. 1056-1066, Nov-Dec 2024. DOI: https://doi.org/10.56499/jppres24.2009_12.6.1056 Original Article Optimization of spray-drying conditions and quality assessment of dry extract from Perilla frutescens (L.) Britton leaves [Optimización de las condiciones de secado por atomización y evaluación de la calidad del extracto seco de hojas de Perilla frutescens (L.) Britton] … Continue reading Spray-drying Perilla frutescens extract optimization
Honey clinical applications in complementary medicine
J. Pharm. Pharmacogn. Res., vol. 12, no. 6, pp. 1040-1055, Nov-Dec 2024. DOI: https://doi.org/10.56499/jppres24.1870_12.6.1040 Review Honey clinical applications in complementary medicine: A critical review [Aplicaciones clínicas de la miel en la medicina complementaria: Una revisión crítica] Thai Hau Koo1, Andee Dzulkarnaen Zakaria2*, Mohd Zulkifli Mustafa3 1Department of Internal Medicine, School of Medical Sciences, Universiti Sains … Continue reading Honey clinical applications in complementary medicine

© 2013-2020 by the authors; licensee JPPRes, Antofagasta, Chile. This journal is an open-access journal distributed under the terms and conditions of the Creative Commons Attribution license-Non Commercial 4.0 international. The content on this site is intended for health professionals. If you are not a health professional, please talk to your doctor about any doubts or concerns regarding your health

Made with ♥ by AVAGAX Studio