J Pharm Pharmacogn Res 2(Suppl. 1): S37, 2014

Special supplement with the abstract book of LATINFARMA 2013

Oral Communication


Guastaldi AC.

Grupo de Biomateriais. Instituto de Química de Araraquara, UNESP, Brasil. Email:

This presentation is directed related to surface modifications by laser beam comparing to various existing processes, such as: mechanical (machining and jetting with abrasives), chemistries (acid attack and passivation) and thermal processes (plasma-spray). The modification of the surface obtained by the laser beam incidence in the surface of the implant cause micro/nanomorphologic structure assembles the equivalent characteristic without leaving vestige of contamination for being a clean, reproducible process and to make possible a larger control of the variables of the process. Commercially pure titanium implants with surfaces modified by laser beam with and without chemical deposition of apatite applied biomechanical and topographical analysis in rabbits. The contemporaneous implantology looks for advances on implants’ surfaces which allow a safer rehabilitation treatment in a lower period of time. Once the implantation used is subjected to the action of complex mechanical efforts and variations of the physical-chemical properties of the way in which is applied. Literature shows that the implant needs a micro/nanomorphologic superficial structure, not only to assure the mechanic anchorage of the bone on its surface, but also to provide bone-interaction, which can be understood as the direct connection between the new-formed bone and the surface of an implant, without the fibrous tissue interposition. However, it is difficult to conclude precisely what causes the increase in bone response to a modified surface, particularly in the HA coated implants, as this process alters the chemistry by the addition of HA, but simultaneously, it may alter the physical-chemical properties, micro and nanoroughness. Moreover, depending on the application process of HA, alteration may occur in the surface area. The research considered here validates its development; thereafter it is characterized with great potential to generate and to transfer Brazilian technology, from a process of ample commercial use. It is treated, thus, of a clear possibility of application of an innovative chemical covering process of bioactive layers in the surfaces of implants, which will facilitate the access to a population socially less attended, reverting, thus, with a notable social character. Finally, the physical chemical properties of the surface are responsible by osseointegration phenomenon and the nanoroughness or nanomorphologic will supply more or less area to occur osseointegration.