J. Pharm. Pharmacogn. Res., vol. 12, no. 4, pp. 624-627, Jul-Aug 2024.
DOI: https://doi.org/10.56499/jppres23.1894_12.4.624
Case Report
Conservative treatment of thyroid abscess in a child with thyroglossal duct cyst
[Tratamiento conservador de absceso tiroideo en una niña con quiste del conducto tirogloso]
Ronny Ronny1, Sony Sutrisno2*
1Department of Radiology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
2Department of Radiology, Faculty of Medicine and Health Sciences, Krida Wacana Christian University, Jakarta, Indonesia.
*E-mail: sony.sutrisno@ukrida.ac.id
Abstract
Thyroid abscesses (TA) are a rare clinical entity in adult and pediatric patients. Less than 50 pediatric cases have been described. While inherently resistant to infection, various risk factors may predispose to thyroidal infection and abscess. This report details the incidental discovery of a thyroglossal duct cyst presenting as TA in a child who presented with a 1-week history of worsening pain and swelling of the right neck along with remittent fever. After clinical examination, laboratory examination, and ultrasound, a diagnosis of TA was made. The patient was administered antibiotics and antithyroid medication alongside supportive care. Surgery was considered in case of deterioration or absence of improvement. After two days of treatment, the patient improved and was discharged after two weeks of treatment. This article reports the incidence of TA, which was precipitated by congenital anatomical abnormality. The conservative treatment of TA using antibiotics was also highlighted.
Keywords: pediatric; thyroglossal duct cyst; thyroid abscess.

Resumen
Los abscesos tiroideos (AT) son una entidad clínica poco frecuente en pacientes adultos y pediátricos. Se han descrito menos de 50 casos pediátricos. Aunque son intrínsecamente resistentes a la infección, diversos factores de riesgo pueden predisponer a la infección y el absceso tiroideos. Este informe detalla el descubrimiento incidental de un quiste del conducto tirogloso que se presenta como AT en una niña que acudió con una historia de 1 semana de empeoramiento del dolor y la hinchazón del cuello derecho junto con fiebre remitente. Tras un examen clínico, de laboratorio y ecográfico, se diagnosticó AT. A la paciente se le administraron antibióticos y medicación antitiroidea junto con cuidados de apoyo. Se consideró la cirugía en caso de deterioro o ausencia de mejoría. Tras dos días de tratamiento, la paciente mejoró y fue dado de alta tras dos semanas de tratamiento. Este artículo informa de la incidencia de AT precipitada por una anomalía anatómica congénita. También se destaca el tratamiento conservador de la AT con antibióticos.
Palabras Clave: absceso tiroideo; pediátrico; quiste conducto tirogloso.

Citation Format: Ronny R, Sutrisno S (2024) Conservative treatment of thyroid abscess in a child with thyroglossal duct cyst. J Pharm Pharmacogn Res 12(4): 624–627. https://doi.org/10.56499/jppres23.1894_12.4.624
References
Akdemir Z, Karaman E, Akdeniz H, Alptekin C, Arslan H (2015) Giant thyroid abscess related to postpartum Brucella infection. Case Rep Infect Dis 2015: 646209. https://doi.org/10.1155/2015/646209
Céspedes C, Duran P, Uribe C, Chahín S, Lema A, Coll M (2013) Thyroid abscess. A case series and literature review. Endocrinol Nutr 60: 190–196. https://doi.org/10.1016/j.endoen.2012.09.003
Deaver MJ, Silman EF, Lotfipour S (2009) Infected thyroglossal duct cyst. West J Emerg Med 10: 205. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729228/
Falhammar H, Wallin G, Calissendorff J (2019) Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes. BMC Endocr Disord 19: 130. https://doi.org/10.1186/s12902-019-0458-0
Lafontaine N, Learoyd D, Farrell S, Wong R (2021) Suppurative thyroiditis: Systematic review and clinical guidance. Clin Endocrinol 95: 253–264. https://doi.org/10.1111/cen.14440
Lesh R, Hellums R, Pichardo P, Wong J, Pellitteri P, Purdy N, Stavrides K, Haugen TW (2023) Thyroid abscess: a case series and literature review. Ear Nose Throat J 1455613221150128. https://doi.org/10.1177/01455613221150128
Maldhure S, Golhar P, Dhawan VB (2023) A case of pediatric thyroid abscess: a rare entity. Indian J Otolaryngol Head Neck Surg 75: 2319–2322. https://doi.org/10.1007/s12070-023-03580-0
Ogunkeyede SA, Ogundoyin OO (2019) Management outcome of thyroglossal cyst in a tertiary health center in Southwest Nigeria. Pan Afr Med J 34: 154. https://doi.org/10.11604/pamj.2019.34.154.18765
Paes JE, Burman KD, Cohen J, Franklyn J, McHenry CR, Shoham S, Kloos RT (2010) Acute bacterial suppurative thyroiditis: A clinical review and expert opinion. Thyroid 20: 247–255. https://doi.org/10.1089/thy.2008.0146
Tapasak B, Nguyen DK, Cervantes SS (2022) Infected thyroglossal duct cyst in a neonate: A report of a rare case. Am J Case Rep 23: e936659. https://doi.org/10.12659/AJCR.936659
Yedla N, Pirela D, Manzano A, Tuda C, Presti SL (2018) Thyroid abscess: challenges in diagnosis and management. J Investig Med High Impact Case Rep 6: 2324709618778709. https://doi.org/10.1177/2324709618778709
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