Pharmacognostical studies on Ziziphora clinopodioides

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J Pharm Pharmacogn Res 5(6): 354-364, 2017. Original Article | Artículo Original Pharmacognostical and phytochemical studies on Ziziphora clinopodioides Lam. – A Kazakh and Uygur ethnomedicinal plant [Estudios farmacognósticos y fitoquímicos sobre Ziziphora clinopodioides Lam. – Una planta etnomedicinal kazaja y uygur] Yun Zhu1, Yuan Xiong1, Hehua Wang2, Peng Li1* 1School of Pharmacy, Shihezi University/Key Laboratory of Xinjiang Endemic … Continue reading Pharmacognostical studies on Ziziphora clinopodioides

J Pharm Pharmacogn Res 5(6): 354-364, 2017.

Original Article | Artículo Original

Pharmacognostical and phytochemical studies on Ziziphora clinopodioides Lam. – A Kazakh and Uygur ethnomedicinal plant

[Estudios farmacognósticos y fitoquímicos sobre Ziziphora clinopodioides Lam. – Una planta etnomedicinal kazaja y uygur]

Yun Zhu1, Yuan Xiong1, Hehua Wang2, Peng Li1*

1School of Pharmacy, Shihezi University/Key Laboratory of Xinjiang Endemic Phytomedicine Resources Ministry of Education, Shihezi Xinjiang 832002, PR China.
2Hebi City People’s Hospital Infection Management Section, Hebi Henan 458030, PR China.

*E-mail: whitecloud2002001@163.com

Abstract

Context: Ziziphora clinopodioides Lam. (Lamiaceae) is an annual or perennial herb or subshrub widely distributed from the Mediterranean to central Asia and Afghanistan. In Xinjiang, China, the whole herb has been used in traditional Kazakh and Uygur medicines as anti-febrile and detoxicating drug.

Aims: To characterize macroscopical, microscopically of the overground part of the Z. clinopodioides, explore and establish the macro-morphology, micro-morphology, quality and physicochemical parameters standards for this plant.

Methods: Pharmacognostical and phytochemical investigations were conducted in terms of macroscopic, microscopic and preliminary phytochemical parameters.

Results: The vegetable material can be identified by structural features of the flowers, structural characteristics of the stem, specific pale brown hesperidin can be regarded as identification character. This crude drug showed the characteristic physicochemical values like total ash (7%), insoluble ash (1.3%), water soluble ash (3.7%), moisture (7.5%). The ethanolic extract contained flavonoids, organic acids, alkaloids, and glycosides.

Conclusions: Various pharmacognostical characters that observed in this study can be an effective supplement to further research of this ethnomedicinal plant. Meanwhile, the results of this paper deal with pharmacognostical studies on the Ziziphora clinopodioides in an attempt to mitigate the adulteration to the crude drug.

Keywords: micromorphology; morphology; pharmacognostical identification; Ziziphora clinopodioides.

Resumen

Contexto: Ziziphora clinopodioides Lam. (Lamiaceae) es una hierba anual o perenne o arbusto ampliamente distribuida desde el Mediterráneo a Asia central y Afganistán. En Xinjiang, China, la hierba entera se ha utilizado en las medicinas tradicionales de Kazajistán y Uygur como droga anti-febril y desintoxicante.

Objetivos: Caracterizar macroscópicamente y microscópicamente la parte aérea de Z. clinopodioides, explorar y establecer la macro-morfología, la micro-morfología, la calidad y los parámetros físico-químicos estándares para esta planta.

Métodos: Las investigaciones farmacognósticas y fitoquímicas se realizaron en términos de parámetros macroscópicos, microscópicos y fitoquímicos preliminares.

Resultados: El material vegetal pudo ser identificado por las características estructurales de las flores, las características estructurales del tallo, específico color marrón pálido hesperidina puede ser considerado como carácter de identificación. Esta droga cruda bruto mostró los valores fisicoquímicos característicos como cenizas totales (7%), cenizas insolubles (1,3%), cenizas solubles en agua (3,7%) y humedad (7,5%). El extracto etanólico contenía flavonoides, ácidos orgánicos, alcaloides y glucósidos.

Conclusiones: Varios caracteres farmacognósticos que se observaron en este estudio pueden ser un suplemento efectivo para investigaciones posteriores de esta planta etnomedicinal. Mientras tanto, los resultados de este trabajo se refieren a estudios farmacognósticos sobre la Ziziphora clinopodioides en un intento por mitigar la adulteración de la droga cruda.

Palabras Clave: identificación farmacognóstica; micromorfología; morfología; Ziziphora clinopodioides.

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Citation Format: Zhu Y, Xiong Y, Wang H, Li P (2017) Pharmacognostical and phytochemical studies on Ziziphora clinopodioides Lam. – A Kazakh and Uygur ethno-medicinal plant. J Pharm Pharmacogn Res 5(6): 354–364.

© 2017 Journal of Pharmacy & Pharmacognosy Research (JPPRes)

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