J Pharm Pharmacogn Res 3(suppl. 1): S128, 2015

Proceedings of the 4th International Symposium on Pharmacology of Natural Products FAPRONATURA 2015  September 21st-25th, 2015; Cuban Society of Pharmacology. Topes de Collantes, Sancti Spiritus, Cuba.



Morales M1, Galdós MC1, López I1, Vázquez R2, Piña JC1.

1Camagüey Medical University. Carretera Central oeste Km 4 ½, Camagüey, Cuba. E-mail:
2“Tte. Tomás Rojas” Teaching Polyclinic. Céspedes, Calle 31 Esquina 20, Camagüey, Cuba. E-mail:


Introduction: Bixa orellana L. is a plant that grows in Cuba, to which medicinal properties are attributed. Material and Methods: An experimental study was carried out in order to determine the antimicrobial action of ethanolic extracts and dyes of B. orellana leaves against Candida albicans, Staphylococcus aureus, Escherichia coli, and Pseudomona aeruginosa. The macrodilution method was used and the concentration minimum germicide was determined expressed in dilutions. Stumps of international reference from American Type Culture Collection of E. coli, S. aureus, P. aeruginosa and C. albicans were used. Results: The dyes to 10% and 20% of the leaf showed inhibitory activity against S. aureus in dilutions up to 1:8 and 1:32 respectively; in E. coli; the dye to 10% presented activity up to 1:8, the dyes were not active against P. aeruginosa and C. albicans. The flowing extract to 50% showed inhibitory activity in front of S. aureus up to 1:4. The flowing extract to 50% and the dyes of the leaf to 10% and 20% was active in front of S. aureus to inferior concentrations with regard to the rest of the microorganisms, but they lacked antimicrobial activity in front of C. albicans and P. aeruginosa. Conclusions: S. aureus turned out to be the most sensitive germ to the pharmaceutical forms studied to smaller concentrations minimum germicides expressed in the dilutions. The dye to 10% showed a bigger spectrum of antimicrobial activity. The dye to 20% was the most effective.


Citation Format: Morales M, Galdós MC, López I, Vázquez R, Piña JC (2015) Antimicrobial action of Bixa orellana L. [Abstract]. In: Proceedings of the FAPRONATURA 2015; 2015 Sep 21-25; Topes de Collantes, Sancti Spiritus: CSF. J Pharm Pharmacogn Res 3(Suppl. 1): S128. Abstract nr PNAI-36.