Tag Archives: phytochemicals

Phytochemical and antioxidant analysis of Ecuadorian’s Malva

J. Pharm. Pharmacogn. Res., vol. 10, no. 3, pp. 551-561, May-June 2022.

Original Article

Phytochemical composition and antioxidant capacity of the aqueous extracts of Malva sylvestris L. and Malva pseudolavatera Webb & Berthel.

[Composición fitoquímica y capacidad antioxidante de los extractos acuosos de Malva sylvestris L. y Malva pseudolavatera Webb & Berthel.]

Glenda M. Sarmiento Tomala1*, Yamilet I. Gutiérrez Gaitén2, René Delgado Hernández3, Zoraida del C. Burbano Gómez1, Pilar A. Soledispa Cañarte1, Nicole D. Jaramillo Sarmiento4, Leonardo A. Vargas Prias5

1Faculty of Chemical Sciences “Salvador Allende”. University of Guayaquil. Guayaquil, Ecuador

2Department of Pharmacy. Institute of Pharmacy and Food. University of Havana. Havana, Cuba.

3Center for Research and Biological Evaluations. Institute of Pharmacy and Food. University of Havana. Havana, Cuba.

4Ecuadorian Consortium of Telecommunications S.A (CONECEL). Ecuador.

5National Telecommunications Corporation, Public Company. Ecuador.

*E-mail: glenda.sarmientot@ug.edu.ec

Abstract

Context: Malva spp. have been widely used in the world as traditional remedies. In Ecuadorian markers Malva sylvestris and Malva pseudolavatera are the species most commercialized. However, the scientific information about M. pseudolavatera is little.

Aims: To determine the chemical composition and antioxidant capacity of the aqueous extracts of the leaves of both species.

Methods: Aqueous extracts were partitioned with butanol and the fractions obtained were analyzed by GC/MS. Total extracts were evaluated as antioxidants using FRAP, DPPH and ABTS assays.

Results: Differences in the chemical composition were found between the extracts. Both extracts showed the presence of polysaccharides, phenolic acids and fatty acids, but in M. sylvestris were identified polyols, which there was not observed in M. pseudolavatera. The aqueous extracts showed free radical scavenging and ferric reducing power capacities in vitro assays, being M. sylvestris the most promissory antioxidant, possibly due to the presence of polyols in the extract. In the present research were reported 39 phytochemical compounds by first time for the specie M. pseudolavatera.

Conclusions: Aqueous extracts of the leaves of M. sylvestris and M. pseudolavatera showed antioxidant capacity associated with the presence of phenolic acids, polysaccharides and flavonoids in the extracts.

Keywords: antioxidant; gas chromatography; Malva pseudolavatera; Malva sylvestris; phytochemicals.

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Resumen

Contexto: Las especies de Malva son muy empleadas mundialmente como remedios tradicionales. En los mercados ecuatorianos se comercializa mayoritariamente las especies Malva sylvestris y Malva pseudolavatera, sin embargo, sobre esta última especie la información científica es escasa.

Objetivos: Determinar la composición química y capacidad antioxidante de los extractos acuosos de las hojas de ambas especies.

Métodos: Los extractos acuosos fueron particionados con butanol para posterior análisis por CG/EM. La capacidad antioxidante de los extractos totales fue evaluada mediante los ensayos de FRAP, DPPH y ABTS.

Resultados: Se encontraron diferencias en la composición química de los extractos. En ambas especies se observó la presencia de polisácaridos, ácidos fenólicos y ácidos grasos; sin embargo, en M. sylvestris se identificaron polioles que no fueron observados en M. pseudolavatera. Los extractos acuosos mostraron capacidad secuestradora de radicales y poder reductor del hierro en los ensayos in vitro realizados. M. sylvestris resultó ser la especie más promisoria como antioxidante, probablemente asociado a la presencia de polioles. En el estudio se reportaron, por primera vez, 39 compuestos químicos para la especie M. pseudolavatera.

Conclusiones: Los extractos acuosos de las hojas de M. sylvestris y M. pseudolavatera mostraron capacidad antioxidante asociada con la presencia de ácidos fenólicos, polisacáridos y flavonoides en los extractos.

Palabras Clave: antioxidante; cromatografía de gases; fitoquímica; Malva pseudolavatera; Malva sylvestris.

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Citation Format: Sarmiento GM, Gutiérrez YI, Delgado R, Burbano ZC, Soledispa PA, Jaramillo ND, Vargas LA (2022) Phytochemical composition and antioxidant capacity of the aqueous extracts of Malva sylvestris L. and Malva pseudolavatera Webb & Berthel. J Pharm Pharmacogn Res 10(3): 551–561.
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