Tag Archives: phytotherapy

Phytotherapy against COVID-19 and risks of intoxication

J. Pharm. Pharmacogn. Res., vol. 10, no. 3, pp. 357-386, May-June 2022.

Original Article

Phytotherapy in response to COVID-19 and risks of intoxication: A field study in the city of Meknes (Morocco)

[Fitoterapia en respuesta al COVID-19 y riesgos de intoxicación: un estudio de campo en la ciudad de Meknes (Marruecos)]

Mariame Najem*, Jamal Ibijbijen, Laila Nassiri

Environment and Valorisation of Microbial and Plant Resources Unit, Faculty of Sciences, Moulay Ismail University of Meknes, P.O.B: 11201 Meknes, Morocco.

*E-mail: ma.najem@edu.umi.ac.ma, mariamenajem@gmail.com

Abstract

Context: The contagious global pandemic of coronavirus 2019 (COVID-19) has prompted many Moroccans to turn to traditional phytoremedies.

Aims: To highlight the ethnopharmacological information and the risks of intoxication related to the use of herbal medicine to combat COVID-19.

Methods: Through a semi-structured questionnaire and using the “Free listing” technique, an ethnobotanical survey was conducted among 36 herbalists of the Meknes prefecture to collect ethnopharmacological data on species used in the fight against COVID-19. Then, many databases were used to document their pharmacological and toxicological activities.

Results: A total of 36 species in 22 families were reported to be used to prepare traditional recipes against COVID-19. According to the relative frequency index of citation, the species Artemisia herba-alba Asso, Eucalyptus globulus Labill, Syzygium aromaticum (L.) Merr. & L.M. Perry, Citrus limon (L.) Osbeck, and Zingiber officinale Roscoe. were recommended by all respondents and recorded the highest usage values. Based on the value of the plant parts index, leaves were the most used part (PPV = 0.37). Most of the remedies were prepared as infusions and administered orally. The bibliographic research revealed that the plants used have several biological activities and are frequently used to treat respiratory diseases. However, some of them have been reported to be toxic.

Conclusions: Recommended species are endowed with innumerable biological activities. They can be a promising alternative to combat COVID-19. However, their toxic effects require pharmacotoxicological studies to ensure the safety and efficacy of these natural remedies.

Keywords: COVID-19; ethnobotany; herbalism; Morocco; Meknes; phytotherapy; toxicity.

Resumen

Contexto: La contagiosa pandemia mundial del coronavirus 2019 (COVID-19) ha llevado a muchos marroquíes a recurrir a los fitorremedios tradicionales.

Objetivos: Resaltar la información etnofarmacológica y los riesgos de intoxicación relacionados con el uso de fitoterápicos para combatir el COVID-19.

Métodos: A través de un cuestionario semiestructurado y utilizando la técnica de “Listado Libre”, se realizó un relevamiento etnobotánico entre 36 herbolarios de la prefectura de Meknes para recolectar datos etnofarmacológicos sobre especies utilizadas en la lucha contra COVID-19. Luego, se utilizaron muchas bases de datos para documentar sus actividades farmacológicas y toxicológicas.

Resultados: Se informó que un total de 36 especies en 22 familias se utilizaron en la preparación de recetas tradicionales contra COVID-19. Según el índice de frecuencia relativa de citación, las especies Artemisia herba-alba Asso, Eucalyptus globulus Labill, Syzygium aromaticum (L.) Merr. & L.M. Perry, Citrus limon (L.) Osbeck y Zingiber officinale Roscoe. son recomendados por todos los encuestados y registró los valores de uso más altos. Sobre la base del índice del valor de las partes de la planta, las hojas son la parte más utilizada (VPP = 0,37). La mayoría de los remedios se prepararon como infusiones y se administraron por vía oral. La investigación bibliográfica reveló que las plantas utilizadas tienen varias actividades biológicas y se utilizan con frecuencia en el tratamiento de enfermedades respiratorias. Sin embargo, se ha informado que algunos de ellos son tóxicos.

Conclusiones: Las especies recomendadas están dotadas de innumerables actividades biológicas, pueden ser una alternativa prometedora para combatir el COVID-19. Sin embargo, sus efectos tóxicos requieren estudios farmacotoxicológicos para garantizar la seguridad y eficacia de estos remedios naturales.

Palabras Clave: COVID-19; etnobotánica; fitoterapia; herboristería; Marruecos; Meknes; toxicidad.

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Citation Format: Najem M, Ibijbijen J, Nassiri L (2022) Phytotherapy in response to COVID-19 and risks of intoxication: A field study in the city of Meknes (Morocco). J Pharm Pharmacogn Res 10(3): 357–386.
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© 2022 Journal of Pharmacy & Pharmacognosy Research (JPPRes)

Medicinal plants and anemia in Haouz-Rehamna (Morocco)



J Pharm Pharmacogn Res 10(2): 279-302, 2022.

Original Article

Ethnobotanical and ethnopharmacological study of medicinal plants used in the treatment of anemia in the region of Haouz-Rehamna (Morocco)

[Estudio etnobotánico y etnofarmacológico de plantas medicinales utilizadas en el tratamiento de la anemia en la región de Haouz-Rehamna (Marruecos)]

Ouafae Benkhnigue1,2*, Noureddine Chaachouay3, Hamid Khamar1,2, Fatiha El Azzouzi2, Allal Douira2, Lahcen Zidane2

1Department of Botany and Plant Ecology, Scientific Institute, University Mohammed V, B. P. 703, Rabat 10106, Morocco.

2Plant, Animal Productions and Agro-industry Laboratory, Department of Biology, Faculty of Sciences, Ibn Tofail University, B.P. 133 14000, Kenitra, Morocco.

3Higher School of Education and Training, Berrechid, University Hassan, 1st, 50 Rue Ibnou Lhaytham B.P. 577, 26002 Settat, Morocco.

*E-mail: ouafae.benkhnigue@is.um5.ac.ma, benkhnigue@gmail.com

Abstract

Context: The ethnobotanical study of the plants used is of great interest in the medical field. In this perspective, we have carried out this ethnobotanical and ethnopharmacological study, which is part of the development of plant resources traditionally used against anemia in a large region of Middle Atlantic Morocco (Mam-4): Al Haouz-Rehamna.

Aims: To establish a catalog of medicinal plants used in traditional medicine against anemia disease.

Methods: For this purpose, we carried out an ethnobotanical survey using 1700 questionnaire cards during five campaigns (from 2012 to 2017) in the studied field. In addition, the information sought was about the plant including its local name, its part used, its toxicity and, medical practices related. Ethnobotanical indices, such as Use Value (UV), Family Use Value (FUV) and, Plant Part Value (PPV), were determined.

Results: The results allowed us to identify 48 medicinal plants of which 12 were toxic. The inventoried species were distributed in 45 genera and belong to 27 botanical families, of which four predominated in the number of species: Apiaceae, Amaranthaceae, Fabaceae, and Asteraceae. Also, 11 species were traditionally more used as effective plants against anemia: Rubia peregrina, Lens culinaris, Malva sylvestris, Beta vulgaris, Spinacia oleracea, Mercurialis annua, Hibiscus sabdariffa, Corrigiola telephiifolia, Nasturtium officinale, Cistus laurifolius and Armeria mauritanica. The leafy stems were the most used part (PPV = 0.28%) followed by the seed (PPV = 0.26%). These parts were usually used steamed, decocted, and rarely triturated in honey or infused in water. The recipes were administered orally until cured.

Conclusions: The present study established the importance of documenting traditional knowledge about the species of medicinal plants that are used to correct many chronic diseases such as anemia. Analysis of this knowledge has shown that several of the listed plants promoted anti-anemia activity and could become the basis for in-depth scientific investigations.

Keywords: anemia; ethnobotanic; Morocco; pharmacology; phytotherapy; toxicity.

Resumen

Contexto: El estudio etnobotánico de las plantas utilizadas es de gran interés en el ámbito médico. Es en esta perspectiva que hemos llevado a cabo este estudio etnobotánico y etnofarmacológico que forma parte del desarrollo de los recursos vegetales utilizados tradicionalmente contra la anemia en una gran región del Atlántico Medio de Marruecos (Mam-4): Al Haouz-Rehamna.

Objetivos: Establecer un catálogo de plantas medicinales utilizadas en la medicina tradicional contra esta enfermedad.

Métodos: Para ello, se realizó un relevamiento etnobotánico utilizando 1700 fichas de cuestionario durante cinco campañas (de 2012 a 2017). Además, la información buscada era sobre la planta, incluido su nombre local, la parte utilizada, su toxicidad y prácticas médicas relacionadas. Se determinaron los índices etnobotánicos, como el valor de uso (UV), el valor de uso familiar (FUV) y el valor de la parte de la planta (PPV).

Resultados: Se identificaron 48 plantas medicinales de las cuales 12 fueron tóxicas. Las especies inventariadas se distribuían en 45 géneros y pertenecían a 27 familias botánicas, de las cuales cuatro predominaron en el número de especies: Apiaceae, Amaranthaceae, Fabaceae y Asteraceae. Asimismo, tradicionalmente se utilizaban más 11 especies como plantas eficaces contra la anemia: Rubia peregrina, Lens culinaris, Malva sylvestris, Beta vulgaris, Spinacia oleracea, Mercurialis annua, Hibiscus sabdariffa, Corrigiola telephiifolia, Nasturtium officinale, Cistus laurifolius y Armeria mauritanica. Los tallos frondosos fueron la parte más utilizada (PPV = 0.28%) seguido de la semilla (PPV = 0.26%). Estas partes generalmente se usaban al vapor, cocidas y, rara vez, trituradas en miel o infundidas en agua. Las recetas se administraban por vía oral hasta que se curaban.

Conclusiones: El presente estudio estableció la importancia de documentar los conocimientos tradicionales sobre las especies de plantas medicinales que se utilizan para corregir muchas enfermedades crónicas como la anemia. El análisis de este conocimiento ha demostrado que varias de las plantas enumeradas promueven la actividad anti-anemia y podrían convertirse en la base para investigaciones científicas en profundidad.

Palabras Clave: anemia; etnobotánica; farmacología; fitoterapia; Marruecos; toxicidad.

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Citation Format: Benkhnigue O, Chaachouay N, Khamar H, El Azzouzi F, Douira A, Zidane L (2022) Ethnobotanical and ethnopharmacological study of medicinal plants used in the treatment of anemia in the region of Haouz-Rehamna (Morocco). J Pharm Pharmacogn Res 10(2): 279–302.

© 2022 Journal of Pharmacy & Pharmacognosy Research (JPPRes)

Ethnobotanical and agronomical survey of B. cinerea


J Pharm Pharmacogn Res 9(5): 685-694, 2021.

Original article

Ethnobotanical and agronomical survey of Brocchia cinerea (Delile) Vis. plant used by people in the Figuig and Draa-Tafilalet regions, Morocco

[Estudio etnobotánico y agronómico de la planta Brocchia cinerea (Delile) Vis. utilizada por personas en las regiones de Figuig y Draa-Tafilalet, Marruecos]

Nisrine Chlif1*, Mohammed Diouri2, Noureddine El Messaoudi3, Aissam Sbai1, Amar Bentayeb1

1Team of Physical-Chemistry of Condensed Matter, Chemistry Department, Faculty of Sciences, Moulay Ismail University, BP. 11201 Zitoune Meknes, Morocco.

2Laboratory of Biotechnologies and Bio-resources Utilization (BioVaR), Biology Department, Faculty of Sciences, Moulay Ismail University, Meknes, Morocco.

3Laboratory of Applied Chemistry and Environment, Chemistry Department, Faculty of Sciences, Ibn Zohr University, Agadir, Morocco.

*E-mail: nisrin.chliff@gmail.com

Abstract

Context: As part of the development of the natural heritage of Morocco, an ethnobotanical and agronomic study was conducted in the regions of Figuig and Draa- Tafilalet.

Aims: To collect detailed information about the usage of Brocchia cinerea plant in human therapy and its incorporation into the feed system of livestock.

Methods: The survey was carried out over five months, using semi-structured and structured interviews. A total of 197 interviews with traditional health practitioners and educated villagers were conducted.

Results: Interview results showed that Brocchia cinerea is used in indigenous pharmacopeia to alleviate common diseases symptoms of the digestive system (36%), nervous system (19%), respiratory system (17%), ear, nose and throat (ENT) disorders (8%), and rheumatism (7%). The aerial parts of this plant were the most commonly used (36%), and the most preferred method for the preparation of traditional drugs was a decoction (33%). The results obtained from the agronomical survey show that the milk yield and meat production in ruminants noticeably increase after consumption of this plant.

Conclusions: The data collected may help prevent the loss of traditional knowledge on the use of plants characterizing the ecosystem of these study areas and may constitute preliminary information required for a future phytochemical study on the plants most frequently used. The agronomic survey carried out can help the range managers improve the forage quality by using Brocchia cinerea for the betterment of animal health and productivity.

Keywords: Asteraceae; Brocchia cinerea; Cotula cinerea; medicinal plant; phytotherapy; traditional medicine.

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Resumen

Contexto: Como parte del desarrollo del patrimonio natural de Marruecos, se realizó un estudio etnobotánico y agronómico en las regiones de Figuig y Draa-Tafilalet.

Objetivos: Recopilar información detallada sobre el uso de la planta Brocchia cinerea en la terapia humana y su incorporación al sistema de alimentación del ganado.

Métodos: La encuesta se realizó durante cinco meses, mediante entrevistas estructuradas y semiestructuradas. Se llevaron a cabo un total de 197 entrevistas con profesionales de la salud tradicionales y pobladores educados.

Resultados: Los resultados de la entrevista mostraron que Brocchia cinerea se usa en la farmacopea indígena para aliviar los síntomas de enfermedades comunes del sistema digestivo (36%), sistema nervioso (19%), sistema respiratorio (17%), desórdenes en otorrinolaringología (8%) y reumatismo (7%). Las partes aéreas de esta planta fueron las más utilizadas (36%) y el método más preferido para la preparación de medicamentos tradicionales fue la decocción (33%). Los resultados obtenidos de la encuesta agronómica muestran que el rendimiento de leche y la producción de carne en rumiantes aumentan notablemente después del consumo de esta planta.

Conclusiones: Los datos recolectados pueden ayudar a prevenir la pérdida de conocimiento tradicional sobre el uso de plantas que caracterizan el ecosistema de estas áreas de estudio y pueden constituir información preliminar requerida para un futuro estudio fitoquímico sobre las plantas más utilizadas. La prospección agronómica realizada puede ayudar a los gestores de pastizales a mejorar la calidad del forraje mediante el uso de Brocchia cinerea para mejorar la salud y la productividad de los animales.

Palabras Clave: Asteraceae; Brocchia cinerea; Cotula cinerea; fitoterapia; medicina tradicional; planta medicinal.

This image has an empty alt attribute; its file name is jppres_pdf_free.png
Citation Format: Chlif N, Diouri M, El Messaoudi N, Sbai A, Bentayeb A (2021) Ethnobotanical and agronomical survey of Brocchia cinerea (Delile) Vis. plant used by people in the Figuig and Draa-Tafilalet regions, Morocco. J Pharm Pharmacogn Res 9(5): 685–694.

© 2021 Journal of Pharmacy & Pharmacognosy Research (JPPRes)

Ethnomedicinal plants used in Bni-Leit and Al-Oued districts, Morocco



J Pharm Pharmacogn Res 9(3): 284-312, 2021.

Original Article

Ethnomedicinal and traditional phytotherapeutic plants used in Bouhachem Natural Regional Park (Rif of Morocco): Case of Bni-Leit and Al-Oued districts

[Plantas etnomedicinales y fitoterapéuticas tradicionales utilizadas en el Parque Regional Natural de Bouhachem (Rif de Marruecos): El caso de las comunas rurales de Bni-Leit y Al-Oued]

Mohammed Bachar, Houda ElYacoubi,Lahcen Zidane, Atmane Rochdi*

Laboratory of Natural Resources & Sustainable Development, Faculty of Sciences, Ibn Tofail University, Kenitra, Morocco.

*E-mail: atmane.rochdi@uit.ac.ma; AtmaneRochdi@gmail.com

Abstract

Context: The flora of the Bouhachem Regional Natural Park has been studied by many botanists and ecologists, but the analysis of the medicinal and economic values of these plants is still weak and poorly documented. Within the framework of this study, further investigations will be carried out into the value of indigenous medicinal plants and the documentation of their ethnopharmacological knowledge. In addition, due to their important socio-economic role as a second source of income after agriculture, the evaluation of the commercial activity of aromatic and medicinal plants (AMP) will also be taken into account.

Aims: To evaluate the ethnobotanical and commercialized medicinal plants in north region of Morocco in which traditional medicine is widespread.

Methods: The uses of medicinal plants in traditional phytotherapy were researched through 700 question cards, in Bni-Leit and Al-Oued districts, which are a part of the Naturel Regional Park of Bouhachem. A series of ethnobotanical, economic and sociocultural surveys/interviews were conducted among the local population in the study area, between March 2014 and July 2016.

Results: This Ethnobotanical study identified 101 medicinal plant species belonging to 46 families, of which the most abundant are Lamiaceae (FUV: 1.87). This study also revealed that the leaves are the most used parts of the plant (26%) and that the most remedies are prepared as decoction (27%). Digestive disorders rank first among the diseases treated by these plants with a rate of 21%.

Conclusions: The present study shows that the traditional use of medicinal plants still persists and constitutes a very rich heritage in the northern of Morocco. Therefore, this important indigenous knowledge of medicinal plants would be exploited in pharmaceutical research. It reveals that urgent action is needed to promote a sustainable and best practices to reduce the increasing scale of exploitation of AMPs for commercial use and to draw the attention of Park managers to the preservation of these plants from genetic erosion by a rational management.

Keywords: Bouhachem Park; ethnobotanical; medicinal plants; Moroccan Rif; phytotherapy; Tetouan.

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Resumen

Contexto: La flora del Parque Regional Natural de Bouhachem ha sido estudiada por muchos botánicos y ecologistas, pero el análisis de los valores medicinales y económicos de estas plantas es todavía débil y poco registrado. En el presente estudio, las investigaciones ulteriores se centrarán en el valor de las plantas medicinales autóctonas, la documentación de sus conocimientos etnofarmacológicos y la evaluación de la actividad comercial de las plantas aromáticas y medicinales (AMP) en las dos comunas estudiadas.

Objetivos: Evaluar las plantas medicinales etnobotánicas y comercializadas en la región septentrional de Marruecos, en la que la medicina tradicional está muy extendida.

Métodos: Los usos de las plantas medicinales en la fitoterapia tradicional se investigaron mediante 700 tarjetas de preguntas, en los distritos de Bni-Leit y Al-Oued que forman parte del Parque Regional Natural de Bouhachem. Entre marzo de 2014 y julio de 2016 se realizó una serie de encuestas/entrevistas etnobotánicas, económicas y socioculturales entre la población local de la zona de estudio.

Resultados: En este estudio etnobotánico se identificaron 101 especies de plantas medicinales pertenecientes a 46 familias, de las cuales las más abundantes son las Lamiaceae (FUV: 1,87). Este estudio también reveló que las hojas son las partes más utilizadas de la planta (26%) y que la mayoría de los remedios se preparan en forma de decocción (27%). Los trastornos digestivos ocupan el primer lugar entre las enfermedades tratadas por estas plantas con una tasa del 21%.

Conclusiones: El presente estudio muestra que el uso tradicional de las plantas medicinales aún persiste y constituye un patrimonio muy rico en el norte de Marruecos. Por lo tanto, este importante conocimiento indígena de las plantas medicinales sería explotado en la investigación farmacéutica. Revela que es necesario adoptar medidas urgentes para promover prácticas sostenibles y óptimas a fin de reducir la escala cada vez mayor de la explotación de las AMP para uso comercial y señalar a la atención de los administradores de los parques la preservación de esas plantas de la erosión genética mediante una ordenación racional.

Palabras Clave: etnobotánico; fitoterapia; Parque Bouhachem; plantas medicinales; Rif marroquí; Tetuán.

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Citation Format: Bachar M, ElYacoubi H, Zidane L, Rochdi A (2021) Ethnomedicinal and traditional phytotherapeutic plants used in Bouhachem Natural Regional Park (Rif of Morocco): Case of Bni-Leit and Al-Oued districts. J Pharm Pharmacogn Res 9(3): 284–312.

© 2021 Journal of Pharmacy & Pharmacognosy Research (JPPRes)