J Pharm Pharmacogn Res 13(Supplement 1), (April) 2025
Special Issue
Bioinformatics and Phytobioinformatics: Advancing In Silico Approaches to Revolutionize Modern Healthcare. Part 1.
| IFC (Journal of Pharmacy & Pharmacognosy Research). |
| 1.- Original Article |
Ria Nur Puspa Sari, Fadilah (2025) Machine learning-approaches insights into metabolomics for type 2 diabetes mellitus. [Perspectivas metabolómicas para la diabetes mellitus tipo 2 basadas en aprendizaje automático]. J Pharm Pharmacogn Res 13(suppl. 1): S1–S12. https://doi.org/10.56499/jppres24.2108_13.s1.1  [767 Kb] [ABSTRACT] |
| 2.- Original Article |
| Henny Kasmawati, Ruslin Ruslin, Arfan Arfan, Nurramadhani A.Sida, Agustono Wibowo, Megat Ahmad Kamal Megat Hanafiah, Mohd Fazli Mohammat Yahya (2025) In-depth insights into the antidiabetic activity of Dracaena trifasciata (Prain) Mabb. fractions and subfractions: In vitro and computational studies. [Análisis en profundidad de la actividad antidiabética de fracciones y subfracciones de Dracaena trifasciata (Prain) Mabb.: Estudios in vitro y computacionales]. J Pharm Pharmacogn Res 13(suppl. 1): S13–S26. https://doi.org/10.56499/jppres24.2193_13.s1.13 [1.02 Mb] [ABSTRACT] |
| 3.- Original Article |
| Gugulethu M. Miya, Ayodeji O. Oriola, Pallab Kar, Adebola O. Oyedeji (2025) Isolation and characterization of fatty acid esters from Cyperus marginatus Thunb. leaf, their in vitro biological and in silico molecular docking studies. [Aislamiento y caracterización de ésteres de ácidos grasos de hojas de Cyperus marginatus Thunb., estudios de acoplamiento molecular in silico y biológico in vitro]. J Pharm Pharmacogn Res 13(suppl. 1): S27–S46. https://doi.org/10.56499/jppres24.2109_13.s1.27 [1.62 Mb] [ABSTRACT] |
| 4.- Original Article |
| Aiko Zavira Permana, Naura Luviezka Choirunnisa, Debora Chris Kezia, Edwin Widodo, Happy Kurnia Permatasari, Hikmawan Wahyu Sulistomo, Eviana Nurahmawati, Nik Ahmad N. Nik Malek, Agustina Tri Endharti, Sofy Permana (2025) In silico prediction of MMP-2 pathway related to anticancer effects of Sterculia foetida L. [Predicción in silico de la vía MMP-2 relacionada con los efectos anticancerígenos de Sterculia foetida L.]. J Pharm Pharmacogn Res 13(suppl. 1): S47–S57. https://doi.org/10.56499/jppres24.2110_13.s1.47 [566 Kb] [ABSTRACT] |
| 5.- Original Article |
| Ahmad Najib, Rahmawati, Rezki Amriati Syarif, Hasnaeni, Andi Ummu Aiman, Andi Sakti (2025) Exploration of antitumor compounds in Syzygium oblanceolatum (C.B.Rob.) Merr. stem bark using in silico method. [Exploración de compuestos antitumorales en corteza del tallo de Syzygium oblanceolatum (C.B.Rob.) Merr. utilizando el método in silico]. J Pharm Pharmacogn Res 13(suppl. 1): S58–S66. https://doi.org/10.56499/jppres24.2222_13.s1.58 [566 Kb] [ABSTRACT] |
| 6.- Original Article |
| Silvi Zakiyatul Ilmiyah, Sofy Permana, Edwin Widodo, Eviana Norahmawati, Happy Kurnia Permatasari, Yoshiyuki Kawamoto, Nik Ahmad Nizam Nik Malek, Agustina Tri Endharti (2025) Exploring anti-cancer potential of Anredera cordifolia (Ten.) Steenis leaf compounds against MMP-2 receptor in breast cancer: An in silico approach. [Exploración del potencial anticancerígeno de los compuestos de las hojas de Anredera cordifolia (Ten.) Steenis contra el receptor MMP-2 en el cáncer de mama: Un enfoque in silico]. J Pharm Pharmacogn Res 13(suppl. 1): S67–S82. https://doi.org/10.56499/jppres24.2129_13.s1.s67 [1.59 Mb] [ABSTRACT] |
| 7.- Original Article |
| Ruswanto Ruswanto, Tita Nofianti, Indra Indra, Richa Mardianingrum, Sofa Fajriah, Aska Reisya Aulia, Zahra Putri Handirana, Sheilla Fitriani Zahwa (2025) Modification of 5-fluorouracil with thiourea and benzoyl groups and in silico study on thymidylate synthase enzyme as an anticancer candidate. [Modificación del 5-fluorouracilo con grupos tiourea y benzoilo y estudio in silico de la enzima timidilato sintasa como candidato anticancerígeno]. J Pharm Pharmacogn Res 13(suppl. 1): S83–S99. https://doi.org/10.56499/jppres24.2216_13.s1.83 [1.72 Mb] [ABSTRACT] |
| 8.- Original Article |
| Faris Izzatur Rahman, Anissa Nofita Sari, Khalish Arsy Al Khairy Siregar, Indira Prakoso, Aigia Syahraini, Eka Gunarti Ningsih, Essy Harnelly, Zulkarnain Zulkarnain (2025) Revealing Pogostemon cablin (Blanco) Benth. and Murraya koenigii (L.) Spreng. action targets on AKT1 as papillary thyroid cancer therapy based on bioinformatics approach. [Revelación de las dianas de acción de Pogostemon cablin (Blanco) Benth. y Murraya koenigii (L.) Spreng. sobre AKT1 como terapia del cáncer papilar de tiroides basada en un enfoque bioinformático]. J Pharm Pharmacogn Res 13(suppl. 1): S100–S117. https://doi.org/10.56499/jppres24.2163_13.s1.100 [1.48 Mb] [ABSTRACT] |
| 9.- Original Article |
| Ruri Y. Astari, Sri Winarsih, Dian Handayani, Heni D. Windarwati, Holipah, Bambang Rahardjo (2025) In silico analysis of Ziziphus mauritiana Lam. bioactive compounds targeting GABA receptor and ADMET profiles for potential postpartum depression treatment. [Análisis in silico de compuestos bioactivos de Ziziphus mauritiana Lam. dirigidos al receptor GABA y perfiles ADMET para el posible tratamiento de la depresión posparto]. J Pharm Pharmacogn Res 13(suppl. 1): S118–S128. https://doi.org/10.56499/jppres24.2239_13.s1.118 [511 Kb] [ABSTRACT] |
| 10.- Original Article |
| Marsha A. Amelia, Dini Kesuma, Aguslina Kirtishanti, I Gede A. Sumartha, Maria Claudya (2025) Molecular docking, synthesis, and in vitro activity testing of chalcone derivatives from Boesenbergia rotunda (L.) Mansf. against MCF-7 breast cancer cells. [Acoplamiento molecular, síntesis y actividad in vitro de derivados de chalcona de Boesenbergia rotunda (L.) Mansf. contra células MCF-7 de cáncer de mama]. J Pharm Pharmacogn Res 13(suppl. 1): S129–S139. https://doi.org/10.56499/jppres24.2220_13.s1.129 [1.11 Mb] [ABSTRACT] |
| 11.- Original Article |
| Sutrisno Sutrisno, Maharani Maharani (2025) Network pharmacology and molecular docking of Phaleria macrocarpa (Scheff.) Boerl. bioactive compounds involved in endometriosis pathway. [Farmacología en red y acoplamiento molecular de compuestos bioactivos de Phaleria macrocarpa (Scheff.) Boerl. implicados en la vía de la endometriosis]. J Pharm Pharmacogn Res 13(suppl. 1): S140–S152. https://doi.org/10.56499/jppres24.2238_13.s1.140 [1.10 Mb] [ABSTRACT] |
| 12.- Original Article |
| Abdulrahim A. Alzain, Walaa Ibraheem, Fatima A. Elbadwi, Hagar M. Mohamed, Khaled M. Elamin, Wadah Osman, Asmaa E. Sherif, Tariq M. Ajarba, Ahmed Ashour, Reham M. Samra, Gamal A. Mohamed, Sabrin R.M. Ibrahim (2025) Natural P2Y12 inhibitors as antiplatelet leads: A multi-tool in silico study. [Inhibidores naturales del P2Y12 como fármacos antiplaquetarios: Un estudio in silico con múltiples herramientas]. J Pharm Pharmacogn Res 13(suppl. 1): S153–S165. https://doi.org/10.56499/jppres25.2327_13.s1.153 [938 Kb] [ABSTRACT] |
| 13.- Original Article |
| Ni Putu Linda Laksmiani, Rohmad Yudi Utomo, Riris Istighfari Jenie, Adam Hermawan, Arief Nurrochmad, Edy Meiyanto, Mitsunori Kirihata, Ratna Asmah Susidarti (2025) In silico exploration of diboronocurcumin analogs as anti-breast cancer agents using integrative bioinformatics and molecular docking. [Exploración in silico de análogos de diboronocurcumina como agentes anticánceres de mama mediante bioinformática integrativa y acoplamiento molecular]. J Pharm Pharmacogn Res 13(suppl. 1): S166–S189. https://doi.org/10.56499/jppres24.2267_13.s1.166 [2.49 Mb] [ABSTRACT] |
| 14.- Original Article |
| Neyder Contreras-Puentes, Isabella Manzur-Villalobos, Samuel Vargas-Chico, Antistio Alviz-Amador (2025) In silico evaluation of ginsenoside analogs as β and γ-secretase inhibitors in Alzheimer’s disease. [Evaluación in silico de análogos de ginsenósidos como inhibidores de la β y γ-secretasa en la enfermedad de Alzheimer]. J Pharm Pharmacogn Res 13(suppl. 1): S190–S206. https://doi.org/10.56499/jppres24.2229_13.s1.190 [1.26 Mb] [ABSTRACT] |
| 15.- Original Article |
| Ave Rahman, Tri Widiandani, Ram Kumar Sahu, Retno Widyowati (2025) Phytochemical profiling and tyrosinase inhibitory activity of Illicium verum Hook f.: In vitro and in silico insights. [Perfil fitoquímico y actividad inhibidora de la tirosinasa de Illicium verum Hook f.: información in vitro e in silico]. J Pharm Pharmacogn Res 13(suppl. 1): S207–S231. https://doi.org/10.56499/jppres24.2292_13.s1.207 [2.43 Mb] [ABSTRACT] |
| 16.- Original Article |
| Dwi Andriani, Retno Indrawati Roestamadji, Retno Pudji Rahayu, Noengki Prameswari, Meinar Nur Ashrin, Widyasri Prananingrum, Sularsih Sularsih, Ayulistya Paramita Sutarto (2025) Astaxanthin targets VEGF and FGF2 as accelerators of oral wound healing: An in silico and pharmacokinetic analysis. [La astaxantina dirigida a VEGF y FGF2 como aceleradores de la cicatrización de heridas orales: Un análisis in silico y farmacocinético]. J Pharm Pharmacogn Res 13(suppl. 1): S232–S241. https://doi.org/10.56499/jppres25.2356_13.s1.232 [640 Kb] [ABSTRACT] |
| 17.- Original Article |
| Widhya Aligita, Robbi Anta Suntoro, Ellin Febrina, Aiyi Asnawi, I Ketut Adnyana (2025) In vivo and in silico approaches to investigating the neuroprotective effects of water kefir for Alzheimer’s disease. [Enfoques in vivo e in silico para investigar los efectos neuroprotectores del kéfir de agua para la enfermedad de Alzheimer]. J Pharm Pharmacogn Res 13(suppl. 1): S242–S265. https://doi.org/10.56499/jppres24.2271_13.s1.242 [1.27 Mb] [ABSTRACT] |
| 18.- Original Article |
| Taufik Muhammad Fakih, Dhania Novitasari, Mukh Syaifudin, Edy Meiyanto, Okid Parama Astirin, Muthi’ Ikawati, Muchtaridi Muchtaridi (2025) Computational insights into 131I-labeled hesperidin as a multi-target breast cancer therapeutic. [Perspectivas computacionales sobre la hesperidina marcada con 131I como terapia multidiana contra el cáncer de mama]. J Pharm Pharmacogn Res 13(suppl. 1): S266–S288. https://doi.org/10.56499/jppres24.2295_13.s1.266 [1.69 Mb] [ABSTRACT] |
| 19.- Original Article |
| Gusnia Meilin Gholam, Maheswari Alfira Dwicesaria, I Made Artika, Viol Dhea Kharisma, Ahmad Affan Ali Murtadlo, Sukma Sahadewa, Fara Disa Durry, Arli Aditya Parikesit, Hery Purnobasuki, Ekaterina Volnova, Yury Lysenko, Maksim Rebezov, Dora Dayu Rahma Turista, Arif Nur Muhammad Ansori, Teguh Hari Sucipto (2025) Indonesian herbal compounds as potential inhibitors of Plasmodium falciparum CDPK2: Insights from docking, molecular dynamics, and DFT analysis. [Compuestos herbales indonesios como posibles inhibidores de CDPK2 de Plasmodium falciparum: Perspectivas a partir del acoplamiento, la dinámica molecular y el análisis DFT]. J Pharm Pharmacogn Res 13(suppl. 1): S289–S302. https://doi.org/10.56499/jppres25.2336_13.s1.289 [1.69 Mb] [ABSTRACT] |
| 20.- Original Article |
| Nurul A. R. Putranti, Adya Pramusita, Rini D. Ridwan, Muhammad Luthfi, Diah S. Ernawati, Nastiti F. Ramadhani, Ida B. Narmada, I Gusti A. W. Ardani, Viol D. Kharisma, Achmad Syaifudin, Putri C. Situmorang, Tengku N. E. T. A. Noor, Khairul A. Shariff, Albertus P. Nugraha, Alexander P. Nugraha (2025) Quercetin-3'-O-glucoside and delphinidin-3-O-sambubioside from Hibiscus sabdariffa Linn.: A molecular docking study against pathogen-associated molecular patterns and Toll-like receptors. [Quercetina-3'-O-glucósido y delfinidina-3-O-sambubiósido de Hibiscus sabdariffa Linn.: Estudio de acoplamiento molecular frente a patrones moleculares asociados a patógenos y receptores tipo Toll]. J Pharm Pharmacogn Res 13(suppl. 1): S303–S315. https://doi.org/10.56499/jppres25.2361_13.s1.303 [1.37 Mb] [ABSTRACT] |
| 21.- Original Article |
| Nurina Hasanatuludhhiyah, Arifa Mustika, Viskasari P. Kalanjati, Kautsar U. Haq, Muhammad Miftahussurur, Hirokazu Wakuda, Naoto Uemura (2025) Predicting activities of Clinacanthus nutans (Burm.f.) Lindau metabolites against molecular targets in metabolic dysfunction-associated steatotic liver disease. [Predicción de la actividad de los metabolitos de Clinacanthus nutans (Burm.f.) Lindau frente a dianas moleculares en la enfermedad hepática esteatósica asociada a disfunción metabólica]. J Pharm Pharmacogn Res 13(suppl. 1): S316–S332. https://doi.org/10.56499/jppres24.2246_13.s1.316 [1.18 Mb] [ABSTRACT] |
| 22.- Original Article |
| Biomechy Oktomalioputri, Kevin N. Cuandra, Aldi T. Rahman, Zaki S. Aaliyya, Enrico F. Sihombing, Farah A. Kamila, Daffa Z. Rasendriya, Rania Rofiqa, Muhammad N. Hibatullah, Ajib Z. Alamsyah, Gabriela V.P. Husodho, Muhammad F. Hamka, Vincyia Ghovanni, Fitrah Afdha, Selly Erwina (2025) Novel multi-epitope peptide vaccine design and validation using bioinformatics approach targeting MSP-1 protein of Knowlesi malaria. [Diseño y validación de una nueva vacuna peptídica multiepítopa mediante un enfoque bioinformático dirigido a la proteína MSP-1 del virus de la malaria Knowlesi]. J Pharm Pharmacogn Res 13(suppl. 1): S333–S346. https://doi.org/10.56499/jppres24.2250_13.s1.333 [1.43 Mb] [ABSTRACT] |
| 23.- Original Article |
| Galih S. Putra, Melanny I. Sulistyowaty, Yahmin Yahmin, Sumari Sumari, Rini Retnosari, Siti Marfu’ah, Farida Anwari, Farida Suhud, Dini Kesuma, Burhan Ma'arif, Rudy Mardianto, Adulsman Sukkaew, Takayasu Yamauchi (2025) In silico and in vitro antimalarial activity evaluation of eugenol’s transformation products against Plasmodium falciparum strain 3D7 using the Trager and Jensen method. [Evaluación de la actividad antipalúdica in silico e in vitro de los productos de transformación del eugenol frente a la cepa 3D7 de Plasmodium falciparum mediante el método de Trager y Jensen]. J Pharm Pharmacogn Res 13(suppl. 1): S347–S370. https://doi.org/10.56499/jppres24.2286_13.s1.347 [2.38 Mb] [ABSTRACT] |
| 24.- Original Article |
| Etti S. Siregar, Putri C. Situmorang, Nursahara Pasaribu, Hestia Hairima, Mufida R. Hasibuan (2025) Profiling and potential of Marchantia paleacea Bertol. extract for breast anticancer candidate: GC-MS, LC-MS/MS, and in silico analysis. [Perfil y potencial del extracto de Marchantia paleacea Bertol. como candidato contra el cáncer de mama: GC-MS, LC-MS/MS y análisis in silico]. J Pharm Pharmacogn Res 13(suppl. 1): S371–S393. https://doi.org/10.56499/jppres25.2531_13.s1.371 [1.47 Mb] [ABSTRACT] |