Willingness to participate in clinical trials in Vietnam

J. Pharm. Pharmacogn. Res., vol. 10, no. 5, pp. 791-799, September-October 2022.

Original Article

Willingness to participate in clinical trials: A cross-sectional analysis in Ho Chi Minh City, Vietnam

[Disposición para participar en ensayos clínicos: Un análisis transversal en la ciudad de Ho Chi Minh, Vietnam]

Thoai N. Dang, Tran T.T. Bao, Chau N.D. Quynh, Trung V. Quang*

Faculty of Pharmacy, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, 700000, Vietnam.

*E-mail: trungvq@pnt.edu.vn

Abstract

Context: Clinical trial is an experiment on comparable groups of human beings which evaluates the efficacy of a treatment or medical intervention by comparing the effects with other testing treatments or control treatments. Clinical trials help develop alternative treatment solutions or a preventative method for disease as well as support participants with medical and healthcare services during the trial period. Other benefits of clinical trials include gaining information, ensuring health issues, detecting early disease symptoms, and reducing medical services costs.

Aims: To evaluate willingness to participate (WTP) in clinical trials (CT) in Ho Chi Minh city and examine the factors associated with it.

Methods: A cross-sectional study was conducted through the online sampling method and gathered 581 valid responses during two weeks in February 2022.

Results: Among 581 respondents, 71.6% stated they were willing to participate in CT, while 48.2% stated that they would let their family enroll. WTP in CT was higher in participants of younger age, single, not having children, healthy, and without chronic disease. Vietnamese age was associated with WTP in CT.

Conclusions: Assessing WTP in CT helps state management agencies, organizations and research institutes design suitable CT models and increase the voluntary participation rate in CT.

Keywords: clinical trial; Ho Chi Minh city; public; Vietnam; willingness to participate.

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Resumen

Contexto: El ensayo clínico es un experimento en grupos comparables de seres humanos que evalúan la eficacia de un tratamiento o intervención médica comparando los efectos con otros tratamientos de prueba o tratamientos de control. Los ensayos clínicos ayudan a desarrollar una solución de tratamiento alternativa o un método preventivo para la enfermedad, así como también brindan apoyo a los participantes con servicios médicos y de atención médica durante el período de prueba. Otros beneficios de los ensayos clínicos incluyen obtener información, garantizar problemas de salud, detectar síntomas tempranos de enfermedades y reducir el costo de los servicios médicos.

Objetivos: Evaluar la disposición a participar (WTP) en ensayos clínicos (CT) en la ciudad de Ho Chi Minh y examinar los factores asociados con ella.

Métodos: Se realizó un estudio transversal a través del método de muestreo en línea y se recolectaron 581 respuestas válidas durante dos semanas en febrero de 2022.

Resultados: Entre 581 encuestados, el 71,6% afirmó estar dispuesto a participar en CT mientras que el 48,2% afirmó estar dispuesto a dejar que su familia se inscriba. La DAP en CT fue mayor en participantes de menor edad, solteros, sin hijos, sanos y sin enfermedad crónica. La edad vietnamita se asoció con WTP en CT.

Conclusiones: Evaluar la WTP en CT ayuda a las agencias estatales de gestión, organizaciones e institutos de investigación a diseñar modelos de CT adecuados y aumentar la tasa de participación voluntaria en CT.

Palabras Clave: Ciudad Ho Chi Minh; ensayo clínico; público; Vietnam; voluntad de participar.

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Citation Format: Thoai ND, Tran TTB, Chau NDQ, Trung VQ (2022) Willingness to participate in clinical trials: A cross-sectional analysis in Ho Chi Minh City, Vietnam. J Pharm Pharmacogn Res 10(5): 791–799.
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